A MERN Stack course covers the full-stack development of web applications using MongoDB, Express.js, React, and Node.js. Students learn to create robust backend services with Node.js and Express, manage and query databases with MongoDB, and build interactive and dynamic user interfaces with React. The course emphasizes RESTful API development, state management with Redux, and integration of the frontend and backend for seamless data flow. Key topics also include authentication, deployment, and real-time data handling with WebSockets. Hands-on projects and practical exercises equip students with the skills to develop and deploy full-featured MERN applications.